pAb Rabbit anti-Human Amyloid beta peptide 43

Description: Rabbit anti-human Amyloid beta peptide 43 polyclonal antibody

Purification: Protein G affinity purified

Product Type: Primary antibody

Target Protein: Human Amyloid beta peptide 43

Immunogen: Synthetic full-length human amyloid beta peptide 43 (Ab43)

Specificity: Human Aβ43

Reactivity: Human, others not tested

Host: Rabbit

Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.2

Reconstitution: Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.

Storage: Store at -20oC.

Research Area: Alzheimer’s disease and other neurodegenerative disease

Background: 

Amyloid beta peptides Aβ42 and Aβ40 have been investigated extensively for predicating Alzheimer’s disease.  A recent study on amyloid beta peptide Ab43 in brain showed that Aβ43 is more fibrillogenic than other amyloid beta peptides and could be more useful as a biomarker or therapeutic target for Alzheimer’s disease. 

Since Aβ40, Aβ42 and Aβ43 are different only at the few C-end amino acids, antibody to N-terminal sequence can bind with all three amyloid beta peptides. 

Applications:  

Indirect ELISA: The antibody is reactive to full-length human Aβ43 in indirect ELISA.  It has not been evaluated in sandwich ELISA assay.

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.