mAb anti-Human BPH, YBPH-1

Description: Mouse monoclonal antibody to human benign prostatic hyperplasia (BPH)

Purification: Protein G affinity purified

Product Type: Primary antibody

Target Protein: Human benign prostatic hyperplasia

Immunogen: Human benign prostatic hyperplasia tissue

Fusion Myeloma: Sp2/0-Ag14

Specificity: Reactive with BPH or human prostate epithelial cells. 

Species Reacitvity: Human, others not tested

Cross-Reactivity:  Does not react with a variety of other human normal tissues.

Host / Isotype: Mouse, IgM Kappa

Formulation: Lyophilized from a solution in 0.01M PBS, pH7.2

Reconstitution: Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.

Storage: Store at -20^oC

Research Area: Oncology

Background:  

Benign prostatic hyperplasia (BPH) is the benign enlargement of prostate.  In senior males, BPH is a very common phenomenon.  Like prostate cancer, BPH can cause frequent urination, urinary hesitancy and dysuria, but does not result in cancer.  Since it is difficult to distinguish BPH from early stage prostate cancer based on symptoms, identification of specific markers for differentiating prostate cancer from BPH has been an imperative task.

Application: 

Immunohistochemistry:

This antibody reacts with BPH tissue, human prostate epithelial cells, and reacts with well to moderately differentiated prostate tissue.

The antibody does not react with non-prostate tissue, or malignant prostate tissue.

In rare cases, the antibody reacts with poorly differentiated prostate tissue.

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.