mAb anti-Human IL-2, 5A8,

Description: Mouse monoclonal antibody to human Interleikin-2 (IL-2)

Purification: Protein G affinity purified

Product Type: Primary antibody, detection antibody in matched antibody pair.

Target Protein: Human IL-2

Immunogen: Recombinant human IL-2(15.5kDa)

Fusion Myeloma: Sp2/0-Ag14

Specificity: Reactive to recombinant human IL-2.

Species Reactivity: Human, cross-reactivity with other species has not been evaluated.

Host / Isotype: Mouse, IgG2b Kappa

Formulation: Lyophilized in 0.01M PBS, pH 7.2

Reconstitution: Double distilled water is recommended to adjust the final concentration to 1.00 mg/mL.

Storage: Store at -20oC. Avoid repeated freeze and thaw cycles.

Research Area: Cytokine, adapted immunity

Background:

Interleukin 2 (IL-2) is the cytokine secreted by T-cells immediately after the T cell receptors are activated by the binding of foreign antigens.  The cytokine stimulates the growth, proliferation and differentiation of naïve T-cells into “effecter T-cells”, promotes the survival of antigen specific “memory T-cell”, and stimulates the maturation of “regulatory T-cells”.  The cytokine is crucial for the development of adapted immunity, immune memory and the modulation of auto-immunity.

Applications:

ELISA: mAb clone 5A8 can be used as detection antibody to detect recombinant human IL-2 in ELISA when clone 9F9 (MO-C40032B) is used as capture antibody.   Clone 5A8 and clone 9F9 can be used reversely as capture (5A8) and detection (9F9) antibody as well.

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.