mAb anti-HEV, S-13

Description: Mouse monoclonal antibody (mAb) to human hepatitis E virus (HEV) antigen encoded by open reading frame three (ORF3)

Purification: Protein G affinity purified

Product Type: Primary antibody

Target Protein: Human hepatitis E virus (HEV) ORF3 antigen

Immunogen: The immunogen is a highly antigenic polypeptide consisting of at least 30 amino acids encoded by ORF3 region of a Chinese HEV strain.

Fusion Myeloma: Sp2/0-Ag14

Species Reactivity: Human hepatitis E virus, others not tested

Cross-Reactivity: No reactivity with HCV-S, HCV-NS3, HCV-NS4

Host / Isotype: Mouse, IgM Kappa

Formulation: Lyophilized

Reconstitution: Double distilled water is recommended to adjust the final concentration to 1.00mg/mL

Storage: Store at -20^oC

Research Area: Virology

Background:  

Type E hepatitis virus (HEV) is transmitted through fecal-oral route.  In developing country with hot climate, HEV outbreak is common with a high mortality in pregnant woman. The virus has a 7.6kb positive sense single strained RNA genome enclosed in a capsid without envelope.   There are three open reading frames (ORFs) on HEV genome.  ORF1 encodes protease, methyl-transferase, helicase and replicase.  ORF2 encodes capsid protein.  The function of the protein encoded by ORF3 is undefined.

Application: 

ELISA: React with immunogen.

References: 

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.