mAb anti-hCG-α, CH7

Description: Mouse monoclonal antibody to human chorionic gonadotropin alpha subunit (hCG-α)

Purification: Protein G affinity purified

Product Type: Primary antibody

Target Protein: hCG-α

Immunogen: Purified human chorionic gonadotropin

Fusion Myeloma: Sp2/0-Ag14

Specificity: Reactive to hCG-α

Species Reacitvity: Human, others not tested

Host / Isotype: Mouse, IgG1 Kappa

Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.2

Reconstitution: Double distillated water is recommended to adjust the final concentration to 1.00 mg/mL.

Storage: Store at -20^oC

Research Area: Hormone, pregnancy

Background: 

Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by placenta after conception.  hCG is comprised of an a subunit with 92 amino acids and a b subunit with 245 amino acids.  The a subunit is identical to that of LH (Luteinizing hormone), FSH (Follicle stimulating hormone) and TSH (Thyroid stimulating hormone).  hCG sustains corpus luteum, stimulates progesterone secretion, hence is critical to early fetal development.  It has also been reported that hCG plays a role in the development of fetal tolerance to maternal immunity.  hCG is the most sensitive biomarker for pregnancy.

Application: 

ELISA

Affinity purification of HCG

Immuno-precipitation

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.