Rat anti-Mouse CD8, JXYT8

Description: Rat monoclonal antibody to mouse cluster of differentiation 8 (CD8) antigen

Product Type: Primary antibody

Target Protein: Murine T-cell surface antigen CD8 marker

Immunogen: Mouse cytolytic T-lymphocytes

Specificity: Reactive with mouse T-cell surface antigen CD8 marker

Species Reactivity: Mouse, others not tested

Host / Isotype: Rat, IgM

Formulation: Lyophilized from a solution in 0.01M PBS pH7.2

Reconstitution: Double distillated water is recommended to adjust the final concentration to 1.00 mg/mL.

Storage: Store at -20^oC

Research Area: Immunology

Background: 

CD8 is a transmembrane glycoprotein receptor at the surface of cytotoxic T cell, natural killer cells and dendritic cells.  CD8 binds major histocompatibility complex class I (MHC I) and arguments T cell activation by associating with T cell receptor.  It plays an important role in the recognision and destruction of virally infected cells and tumour cells.

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.