mAb anti-Human Free PSA, 108, Capture

Description: Mouse monoclonal antibody to human free prostate specific antigen (fPSA)

Purification: Protein G affinity purified

Product Type: Primary antibody - Capture antibody in matched antibody pair

Target Protein: Human free PSA

Immunogen: Purified human PSA

Fusion Myeloma: Sp2/0-Ag14

Specificity: This monoclonal antibody reacts with human free PSA, but does not react with complexed PSA. 

Species Reacitvity: Human, others not tested

Host / Isotype: Mouse, IgG2a Kappa

Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.2

Reconstitution: Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.

Storage: Store at -20^oC

Research Area: Oncology

Background:  

Free prostate specific antigen (fPSA) is the unbounded form of PSA.   Study has shown that low percentage of fPSA in total PSA (tPSA) is associated with high risk of prostate cancer.   Using percentage of fPSA in tPSA can enhance the predication of prostate cancer and avoid unnecessary biopsies in prostate screen.

Application:

ELISA:  This monoclonal antibody can be used as capture antibody in a sandwich ELISA for human free PSA detection in combination with a HRP-conjugated tracer antibody (Cat. No.: MO-T40052T) that is derived from PSA mAb clone 103 (Cat. No.: MO-T40052A).

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.