mAb anti-Human M-CSF, 21

Description: Mouse monoclonal antibody to human Macrophage Colony Stimulating Factor (M-CSF)

Purification: Protein G affinity purified

Product Type: Primary antibody

Target Protein: Human M-CSF

Immunogen: Purified recombinant human M-CSF (rhM-CSF)

Fusion Myeloma: Sp2/0-Ag14

Specificity: This monoclonal antibody is specifically reactive to human M-CSF.

Species Reactivity: Human, others not tested.

Cross-reactivity: Does not cross react with BSA or other human cytokines tested such as IL-1β, IL-8, IL-16, EGF, G-CSFR, GM-CSF, MCP-1, MCP-3, TGF-β and TNF-α.

Host / Isotype: Mouse, IgG2a Kappa

Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.2

Reconstitution: Double distilled water is recommended to adjust the final concentration to 1.00 mg/mL.

Storage: Store at -20oC

Research Area: Cytokine, Growth Factor

Background:

Macrophage/monocyte colony stimulating factor (M-CSF) is a hematopoietic factor for macrophages, monocytes and bone marrow progenitor cells and also promotes the phogocytic activity of these cells.  MCSF stimulates bone remodeling through its receptors on osteoclasts. MCSF and its receptor are also implicated with the normal development and neoplastic growth of mammary gland.  High level of MCSF is necessary for embryonic implantation and placental development.

Applications: 

ELISA: React with M-CSF in ELISA

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.