Description: Rabbit anti-mouse voltage-gated potassium channel (Kv) 4.3 polyclonal antibody
Purification: Protein G affinity purified
Product Type: Primary antibody
Target Protein: Voltage-gated potassium channel Kv4.3
Immunogen: A synthetic peptide (RTTLERYPDT) corresponding to amino acid 55-64 of mouse voltage-gated potassium channel Kv4.3, conjugated with KLH for immunization
Specificity: This antibody is reactive to the 74kDa mouse Kv4.3 in mouse brain tissue extract on Western blot.
Species Reacitvity: Mouse and other species with consensus Kv4.3 sequence (RTTLERYPDT)
Formulation: Lyophilized in pH 7.4, 0.01M PBS
Reconstitution: Double distilled water is recommended to adjust the final concentration to 1.00 mg/mL.
Storage: Store at -20oC
Research Area: Life science research, stem cell factor signalling, cancer research
Kv4.3 is a member of the voltage-gated potassium channel family. Kv4.3 forms complex with K channel interacting protein and regulates the transient potassium efflux and repolarization in cardiac myocytes. Kv4.3 is highly expressed in brain tissue. It is a member of the rapid inactivating A-type Kv channel subfamily and is encoded by KCND3 gene in human. There are two isoforms of this protein with different sizes resulted from alternative splicing.
ELISA: Dilute the antibody 1:500,000 for detection of the peptide coated on ELISA plate.
Western blot: Dilute approx. 1:5,000 for Western blotting to detect the 74kDa mouse Kv4.3 in mouse brain tissue extract.
Fig.1 Western blot analysis of extracts from mouse brain using anti-KV4.3 rabbit whole antiserum.
If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.
|Product Specificity||pAb Rabbit anti-Mouse Kv4.3|